Scientific Director
Department of Biochemistry, University of Oxford, South Parks Rd, Oxford. OX1 3QU
Department of Biochemistry, University of Oxford, South Parks Rd, Oxford. OX1 3QU
The Central Oxford Structural Molecular Imaging Centre (COSMIC) is a state-of-the-art cryo-electron microscopy facility in the Dorothy Crowfoot Hodgkin Building in the centre of Oxford.
TFS Titan Krios 300 kV cryo-TEM with Gatan BioQuantum K3 direct electron detector and energy filter, for high-resolution single particle analysis, cryo-tomography and cryo-STEM tomography
TFS Talos Arctica 200 kV cryo-TEM with TFS Falcon 4i direct electron detector, for high throughput screening of cryo-grids and single particle analysis
TFS Talos F200C TEM with STEM detector, for screening samples using negative staining and cryo-EM, as well as for cryo-tomography and cryo-STEM tomography
Zeiss Crossbeam 350 cryo-FIB-SEM, for cryo-lamella production and cryo-volume SEM.
Leica Stellaris 5 cryo-confocal microscope for cryo-CLEM, with added laser paths for time-resolved cryo-EM and cryo-super-resolution light microscopy
Two TFS Mark IV Vitrobots for preparing cryo-EM grids
Leica EM GP2 for preparing cryo-EM grids by back-blotting
Leica VCT500 sample transfer system and ACE600 high vacuum sputter coater, for cryo-EM grid transfer and sputtering prior to FIB-SEM
Primo micropatterning device, to optimise cell positioning on EM grids prior to freezing
High performance cluster computing for data storage and processing
Scientific Director
Scientific Advisor
Facility Manager
Staff Scientist – SPA
Staff Scientist – CryoET/CryoCLEM
Scientific Software Support
IT Support
IT Support
Dorothy Crowfoot Hodgkin Building
South Parks Rd
Oxford
OX1 3QU
Phone: 01865 285496
Email: cryoem@bioch.ox.ac.uk (NOT for IT issues – for those, please click on the “Raise an IT ticket” button at the top of the page)
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